Markus Ketteler Selected Research

Sevelamer (RenaGel)

1/2021	Sevelamer Use, Vitamin K Levels, Vascular Calcifications, and Vertebral Fractures in Hemodialysis Patients: Results from the VIKI Study.
1/2020	Characteristics of Patients Who Achieve Serum Phosphorus Control on Sucroferric Oxyhydroxide or Sevelamer Carbonate: A post hoc Analysis of a Phase 3 Study.
1/2019	Effects of sucroferric oxyhydroxide and sevelamer carbonate on chronic kidney disease-mineral bone disorder parameters in dialysis patients.
10/2018	Long-term efficacy and safety of sucroferric oxyhydroxide in African American dialysis patients.
11/2017	One-year efficacy and safety of the iron-based phosphate binder sucroferric oxyhydroxide in patients on peritoneal dialysis.
6/2015	Long-term effects of the iron-based phosphate binder, sucroferric oxyhydroxide, in dialysis patients.
9/2014	A phase III study of the efficacy and safety of a novel iron-based phosphate binder in dialysis patients.
11/2010	Sevelamer carbonate for the treatment of hyperphosphatemia in patients with kidney failure (CKD III - V).
8/2010	Serological cardiovascular and mortality risk predictors in dialysis patients receiving sevelamer: a prospective study.
12/2009	Sevelamer and the bone-vascular axis in chronic kidney disease: bone turnover, inflammation, and calcification regulation.

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Markus Ketteler Research Topics

Disease

40	Chronic Renal Insufficiency 01/2022 - 04/2003
32	Vascular Calcification 01/2022 - 01/2002
23	Hyperphosphatemia 12/2021 - 01/2002
21	Secondary Hyperparathyroidism 01/2020 - 07/2005
19	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 01/2022 - 03/2004
13	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 08/2004
11	Kidney Diseases (Kidney Disease) 01/2019 - 07/2005
10	Inflammation (Inflammations) 01/2022 - 08/2004
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 06/2010
5	Uremia 11/2005 - 05/2003
4	Diarrhea 12/2021 - 09/2014
4	Hypoparathyroidism 01/2021 - 10/2020
4	Diabetes Mellitus 01/2021 - 08/2004
4	Hypercalcemia (Milk Alkali Syndrome) 12/2019 - 12/2005
4	Nausea 10/2018 - 09/2014
4	Calciphylaxis 01/2017 - 01/2008
4	Renal Insufficiency (Renal Failure) 01/2012 - 04/2005
4	Coronary Artery Disease (Coronary Atherosclerosis) 05/2010 - 04/2006
3	Bone Fractures (Bone Fracture) 01/2022 - 05/2008
3	Vomiting 10/2018 - 10/2017
3	Constipation 10/2018 - 09/2014
3	Albuminuria 01/2018 - 03/2002
3	Bone Diseases (Bone Disease) 01/2017 - 03/2004
3	Vitamin K Deficiency 09/2014 - 02/2011
3	Neoplasms (Cancer) 05/2013 - 10/2010
3	Fibrosis (Cirrhosis) 02/2010 - 04/2003
3	Calcinosis 06/2009 - 06/2007
3	Atherosclerosis 06/2009 - 11/2005
2	Heart Failure 01/2021 - 11/2005
2	Bone Resorption 01/2019 - 12/2011
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018 - 03/2005
2	Wounds and Injuries (Trauma) 01/2017 - 03/2011
2	Osteoporosis 01/2017 - 12/2011
2	Hypertension (High Blood Pressure) 09/2015 - 04/2006
2	Pain (Aches) 12/2011 - 03/2002
2	Atrial Fibrillation 10/2011 - 02/2010
2	Atherosclerotic Plaque (Atheroma) 06/2009 - 11/2005
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2008 - 04/2006
2	Aortic Valve Stenosis (Aortic Stenosis) 01/2008 - 05/2007
2	Glomerulonephritis 09/2004 - 04/2003
2	Nephritis 03/2002 - 03/2002
1	Hyperglycemia 01/2022
1	Drug-Related Side Effects and Adverse Reactions 07/2021
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2021
1	Nephrocalcinosis 01/2021
1	Nephrolithiasis 01/2021
1	Cardiac Arrhythmias (Arrythmia) 01/2021
1	Iron Overload 01/2020

Drug/Important Bio-Agent (IBA)

31	Phosphates (Orthophosphate)IBA 12/2021 - 01/2002
27	CalciumIBA 01/2021 - 01/2002
21	MineralsIBA 01/2021 - 11/2005
18	alpha-2-HS-GlycoproteinIBA 01/2017 - 03/2003
13	Phosphorus (Red Phosphorus)IBA 07/2021 - 08/2004
13	Sevelamer (RenaGel)FDA Link 01/2021 - 08/2004
11	Biomarkers (Surrogate Marker)IBA 01/2019 - 04/2006
10	Vitamin K FDA Link 01/2022 - 01/2008
10	Parathyroid Hormone (Parathormone)IBA 10/2021 - 05/2012
10	Vitamin D FDA LinkGeneric 01/2021 - 10/2010
8	sucroferric oxyhydroxideIBA 12/2021 - 06/2015
7	Matrix Gla ProteinIBA 01/2017 - 01/2002
6	paricalcitol (Zemplar)FDA Link 04/2014 - 01/2011
5	Cinacalcet (Sensipar)FDA Link 10/2017 - 05/2012
4	IronIBA 12/2021 - 10/2018
4	Proteins (Proteins, Gene)FDA Link 11/2013 - 05/2003
4	Glycoproteins (Glycoprotein)IBA 05/2007 - 01/2002
3	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2017 - 10/2010
3	Pharmaceutical PreparationsIBA 09/2016 - 01/2011
3	Biological ProductsIBA 04/2013 - 03/2005
2	Niacinamide (Nicotinamide)FDA LinkGeneric 03/2021 - 01/2020
2	SNF472IBA 01/2021 - 01/2020
2	Calcifediol (Calcidiol)FDA Link 12/2019 - 01/2011
2	AntibodiesIBA 08/2019 - 04/2013
2	etelcalcetide hydrochlorideIBA 10/2017 - 10/2017
2	Triglycerides (Triacylglycerol)IBA 09/2015 - 06/2010
2	Uremic ToxinsIBA 03/2014 - 11/2005
2	Immunosuppressive Agents (Immunosuppressants)IBA 12/2011 - 03/2004
2	GlucocorticoidsIBA 12/2011 - 03/2004
2	Angiotensin IIIBA 02/2010 - 04/2003
2	ApolipoproteinsIBA 06/2009 - 11/2005
2	LipidsIBA 06/2009 - 01/2008
2	N 30IBA 01/2008 - 03/2005
2	CholesterolIBA 04/2006 - 11/2005
2	FetuinsIBA 11/2005 - 01/2002
2	CytokinesIBA 04/2005 - 04/2003
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022
1	Contrast MediaIBA 01/2022
1	Angiotensin Receptor AntagonistsIBA 01/2022
1	Warfarin (Coumadin)FDA LinkGeneric 12/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2020
1	ferric citrateIBA 01/2020
1	ferrous sulfate FDA Link 01/2020
1	Methylcellulose (BFL)IBA 01/2020
1	tenapanorIBA 01/2020

Therapy/Procedure

18	Renal Dialysis (Hemodialysis) 03/2021 - 04/2005
12	Therapeutics 12/2021 - 07/2008
3	Kidney Transplantation 12/2011 - 03/2004
2	Oral Administration 01/2021 - 01/2020
2	Peritoneal Dialysis 06/2015 - 09/2014
2	Electric Countershock (Cardioversion) 10/2011 - 02/2010
2	Nephrectomy 06/2009 - 06/2007